Stem Cell Culture Media Improves EAE MStranslate April 11, 2016 Research, Stem Cells, Treatments Research Summary: Conditioned Medium from the Stem Cells of Human Exfoliated Deciduous Teeth Ameliorates Experimental Autoimmune Encephalomyelitis The background Current MS therapies mostly work to suppress...
Gut Microbiome Alters Myelination MStranslate April 6, 2016 Research, Treatments Research Summary: Regulation of prefrontal cortex myelination by the microbiota The Background In recent times, there has been an increasing focus placed on the role that the gut microbiome (composed of...
Natalizumab, B cells and Multiple Sclerosis MStranslate March 29, 2016 B Cells, Basic Sciences, Natalizumab, Research, Treatments Research Summary: Cutting Edge: Integrin a4 is required for regulatory B cell control of experimental autoimmune encephalomyelitis The background For a long time, multiple sclerosis was regarded as an...
Remyelination in MS: Novoron Bioscience MStranslate January 28, 2016 Dr Travis Stiles, Remyelination, Research, Treatments INTERVIEW WITH DR TRAVIS STILES – CEO, NOVORON BIOSCIENCE BD: Brett Drummond, MStranslate TS: Dr Travis Stiles, Novoron Bioscience BD: So welcome everyone to our video today. This video has come...
Melatonin improves outcomes in mouse model of MS MStranslate January 12, 2016 Research, Treatments Research Summary: Melatonin enhances interleukin-10 expression and suppresses chemotaxis to inhibit inflammation in situ and reduce the severity of experimental autoimmune encephalomyelitis The...
Neuroprotection by Novel T Cell Enzyme Inhibitor MStranslate December 9, 2015 Research, Treatments Research Summary: Granzyme B-inhibitor serpina3n induces neuroprotection in vitro and in vivo The background Previous studies have shown that immune cells, known as cytotoxic T cells, are critical in the...
Statement on HSCT for MS: Professor Eva Havrdova MStranslate December 7, 2015 Research, Stem Cells, Treatments Professor Eva Havrdova from Charles University in Prague presented at the recent ECTRIMS Congress, where she discussed the use of Hematopoietic Stem Cell Transplantation (HSCT) for the treatment of multiple...
Determining the Effectiveness of MS Treatments MStranslate November 24, 2015 Social Media, Treatments, Uncategorized A short video summarising the key findings of a recent paper, titled "Inclusion of brain volume loss in a revised measure of 'no evidence of disease activity' (NEDA-4) in relapsing-remitting multiple...
Evaluating Stem Cell Therapy for Progressive MS MStranslate September 22, 2015 Research, Stem Cells, Treatments A publication this week in BMJ Open has outlined a number of studies evaluating the use of stem cell therapy for people with progressive multiple sclerosis. These trials, being conducted by a team from...
MIS416: A Clinical Trial for Secondary Progressive MS MStranslate August 26, 2015 Clinical Trials, Research, Treatments Due to the lack of available treatment options for people with secondary progressive multiple sclerosis (SPMS), the development of novel therapies is vitally important. We sat down with Simon Wilkinson (CEO,...