Multiple Sclerosis: One Disease, Many Causes? MStranslate April 18, 2017 Research, Understanding Science 1 Comment In one of our recent Facebook Live Q&A sessions, I was asked what I thought the biggest hurdle was that needed to be overcome in multiple sclerosis research. Whilst funding problems are something that we...
Mitochondrial Dysfunction & ER Stress in MS MStranslate April 4, 2017 Research, Treatments Research Summary: Rab32 connects ER stress to mitochondrial defects in multiple sclerosis Mitochondria are often referred to as the ‘powerhouses’ of the cell, as they are largely responsible for the...
Regulatory T Cells Promote Remyelination MStranslate March 26, 2017 Remyelination, Research Research Summary: Regulatory T cells promote myelin regeneration in the central nervous system When we think about treating multiple sclerosis, generally there are two main approaches that are discussed. ...
Apitope Announce Positive Peptide Therapy Results MStranslate February 28, 2017 Research, Treatments Imagine you have a dog and a cat and they keep fighting. Solution 1: give one of your pets to someone else. Solution 2: Teach them to get along. Solution 1 describes almost all current MS...
Can Blood Test Determine Type of Multiple Sclerosis? MStranslate February 8, 2017 Basic Sciences, Research Research Summary: Kynurenine pathway metabolomics predicts and provides mechanistic insight into multiple sclerosis progression A recent Australian research breakthrough in multiple sclerosis (MS) has drawn...
HALT-MS: Five Year Study Results MStranslate February 2, 2017 Research, Stem Cells, Treatments Research Summary: High dose immunosuppressive therapy and autologous HCT for relapsing-remitting MS The 5 year results of the HALT-MS trial were today published in Neurology. The HALT-MS clinical trial has...
Case Studies Reveal New Alemtuzumab Side-effects MStranslate January 26, 2017 Alemtuzumab, Research, Treatments Research Summary: Severe B-cell-mediated CNS disease secondary to alemtuzumab therapy A recent report in Lancet Neurology has highlighted two case studies of severe side effects in people with MS receiving...
Dimethyl Fumarate Linked to Liver Injury MStranslate January 17, 2017 Dimethyl fumarate, Research, Treatments Research Summary: Liver injury associated with dimethyl fumarate in multiple sclerosis patients Last Friday, members of the Office of Surveillance and Epidemiology at the US FDA published a brief report in...
Ocrelizumab in Primary Progressive MS MStranslate January 13, 2017 Ocrelizumab, Research, Treatments Research Summary: Ocrelizumab versus Placebo in Primary Progressive Multiple Sclerosis There has been a lot of hype over ocrelizumab as the next ‘wonder drug’ in MS. This has mostly come from the early...
Haemoglobin as Source of Iron Deposits in MS MStranslate December 14, 2016 Research Iron deposits in the brain can be toxic and they have been suggested to be a possible cause of the damage seen in multiple sclerosis (MS). New research from Imperial College London (UCL) has shed more light...
