Mitochondrial Dysfunction & ER Stress in MS MStranslate April 4, 2017 Research, Treatments Research Summary: Rab32 connects ER stress to mitochondrial defects in multiple sclerosis Mitochondria are often referred to as the ‘powerhouses’ of the cell, as they are largely responsible for the...
US FDA Approves Ocrelizumab (Ocrevus) MStranslate March 30, 2017 Ocrelizumab, Treatments Ocrelizumab (Ocrevus) has been granted US FDA approval for the treatment of both replacing-remitting MS (RRMS) and primary progressive MS (PPMS). Ocrelizumab is a monoclonal antibody that targets and...
Apitope Announce Positive Peptide Therapy Results MStranslate February 28, 2017 Research, Treatments Imagine you have a dog and a cat and they keep fighting. Solution 1: give one of your pets to someone else. Solution 2: Teach them to get along. Solution 1 describes almost all current MS...
HALT-MS: Five Year Study Results MStranslate February 2, 2017 Research, Stem Cells, Treatments Research Summary: High dose immunosuppressive therapy and autologous HCT for relapsing-remitting MS The 5 year results of the HALT-MS trial were today published in Neurology. The HALT-MS clinical trial has...
Case Studies Reveal New Alemtuzumab Side-effects MStranslate January 26, 2017 Alemtuzumab, Research, Treatments Research Summary: Severe B-cell-mediated CNS disease secondary to alemtuzumab therapy A recent report in Lancet Neurology has highlighted two case studies of severe side effects in people with MS receiving...
Dimethyl Fumarate Linked to Liver Injury MStranslate January 17, 2017 Dimethyl fumarate, Research, Treatments Research Summary: Liver injury associated with dimethyl fumarate in multiple sclerosis patients Last Friday, members of the Office of Surveillance and Epidemiology at the US FDA published a brief report in...
Ocrelizumab in Primary Progressive MS MStranslate January 13, 2017 Ocrelizumab, Research, Treatments Research Summary: Ocrelizumab versus Placebo in Primary Progressive Multiple Sclerosis There has been a lot of hype over ocrelizumab as the next ‘wonder drug’ in MS. This has mostly come from the early...
MS: Many Stories – The AHSCT Experience – Aziz MStranslate December 19, 2016 MS: Many Stories, Stem Cells, Treatments Personal Experiences of Undergoing AHSCT for Multiple Sclerosis Our "MS: Many Stories" series is all about having members of the MStranslate community share insights into different aspects of their journey...
MS: Many Stories – The AHSCT Experience – Mark MStranslate December 19, 2016 MS: Many Stories, Stem Cells, Treatments Personal Experiences of Undergoing AHSCT for Multiple Sclerosis Our "MS: Many Stories" series is all about having members of the MStranslate community share insights into different aspects of their journey...
High-dose Biotin Clinical Trial Results MStranslate September 13, 2016 Biotin, Clinical Trials, Research, Treatments 1 Comment Research Summary: MD1003 (high-dose biotin) for the treatment of multiple sclerosis: A randomised, double-blind, placebo-controlled study The background Whilst many treatments are now available for...
