Melatonin improves outcomes in mouse model of MS MStranslate January 12, 2016 Research, Treatments Research Summary: Melatonin enhances interleukin-10 expression and suppresses chemotaxis to inhibit inflammation in situ and reduce the severity of experimental autoimmune encephalomyelitis The...
Female Sex Hormones & Multiple Sclerosis MStranslate January 8, 2016 Hormones, Research It has been known for a while that women are more likely to develop multiple sclerosis than men. There have been many studies that have indicated that this may be related to female sex hormones. For...
Effects of High-Dose Vitamin D in PwMS MStranslate January 4, 2016 Lifestyle, Research, Vitamin D Research Summary: Safety and immunologic effects of high- and low-dose cholecalciferol in MS The background There is growing evidence to implicate a potential role for Vitamin D in the development and...
Spinal Cord Lesions & The Risk of Relapse MStranslate December 14, 2015 Neuroimaging, Research Research Summary: Relevance of asymptomatic spinal MRI lesions in patients with multiple sclerosis The background Magnetic resonance imaging or MRI has become a common tool for the diagnosis of multiple...
Neuroprotection by Novel T Cell Enzyme Inhibitor MStranslate December 9, 2015 Research, Treatments Research Summary: Granzyme B-inhibitor serpina3n induces neuroprotection in vitro and in vivo The background Previous studies have shown that immune cells, known as cytotoxic T cells, are critical in the...
Statement on HSCT for MS: Professor Eva Havrdova MStranslate December 7, 2015 Research, Stem Cells, Treatments Professor Eva Havrdova from Charles University in Prague presented at the recent ECTRIMS Congress, where she discussed the use of Hematopoietic Stem Cell Transplantation (HSCT) for the treatment of multiple...
Nr4a1: Is it the Link Between Stress & MS? MStranslate December 1, 2015 Lifestyle, Research The Background Many studies have highlighted a link between stress and multiple sclerosis (MS), including research that has shown that norepinephrine (a regulator of stress) is implicated in the mouse model...
Flaxseed Oil Beneficial for People with MS? MStranslate October 19, 2015 Lifestyle, Research 4 Comments In 2013, the team from Overcoming Multiple Sclerosis (OMS) published a paper as part of the HOLISM research study in the International Journal of Neuroscience. This study showed that the consumption of...
Clinical Trial: MIS416 for Secondary Progressive MS MStranslate October 8, 2015 Clinical Trials, Research A detailed look at the development of Innate Immunotherapeutics' potential Secondary Progressive MS treatment,...
Environmental Factors & MS-related Genes MStranslate September 30, 2015 Genetics, Research The development of the International MS Genetics Consortium has led to the identification of more than 159 genetic variants that are associated with MS. However, we have to ask how important are these and are...