Case Studies Reveal New Alemtuzumab Side-effects MStranslate January 26, 2017 Alemtuzumab, Research, Treatments Research Summary: Severe B-cell-mediated CNS disease secondary to alemtuzumab therapy A recent report in Lancet Neurology has highlighted two case studies of severe side effects in people with MS receiving...
Dimethyl Fumarate Linked to Liver Injury MStranslate January 17, 2017 Dimethyl fumarate, Research, Treatments Research Summary: Liver injury associated with dimethyl fumarate in multiple sclerosis patients Last Friday, members of the Office of Surveillance and Epidemiology at the US FDA published a brief report in...
Ocrelizumab in Primary Progressive MS MStranslate January 13, 2017 Ocrelizumab, Research, Treatments Research Summary: Ocrelizumab versus Placebo in Primary Progressive Multiple Sclerosis There has been a lot of hype over ocrelizumab as the next ‘wonder drug’ in MS. This has mostly come from the early...
Haemoglobin as Source of Iron Deposits in MS MStranslate December 14, 2016 Research Iron deposits in the brain can be toxic and they have been suggested to be a possible cause of the damage seen in multiple sclerosis (MS). New research from Imperial College London (UCL) has shed more light...
MS & Epstein-Barr Virus Update – Part 2 MStranslate November 24, 2016 Epstein-Barr virus, Infection, Research, Understanding Science Research Summary: EBV Infection and Multiple Sclerosis: Lessons from a Marmoset Model Earlier in the week, we discussed the background information about the potential role of Epstein-Barr Virus (EBV) and...
MS & Epstein-Barr Virus Update – Part 1 MStranslate November 21, 2016 Epstein-Barr virus, Infection, Research, Understanding Science 3 Comments Today, we are presenting Part 1 of a two-part update on a role for Epstein-Barr Virus (EBV) in multiple sclerosis (MS). This first part is going to focus on the evidence of why people think that a link may...
MitoQ & Mitochondrial Dysfunction in MS MStranslate November 12, 2016 Research Research Summary: MitoQ, a mitochondria-targeted antioxidant, delays disease progression and alleviates pathogenesis in an experimental autoimmune encephalomyelitis mouse model of multiple sclerosis The...
Monoclonal Antibodies for MS Treatments MStranslate October 20, 2016 Research, Understanding Science By Brett Drummond What’s in a name? I was recently asked a question: “Why do all of the new MS drugs end in mab? Does that mean something?”. The answer is yes and it’s probably worth...
Rates of MS Progression: Dr Tomas Kalincik (MSBase) MStranslate October 11, 2016 Q&A, Research Upon his return from ECTRIMS 2016, Dr Tomas Kalincik from the Melbourne Brain Centre at Royal Melbourne Hospital spoke to MStranslate about recently published research by MSBase investigators. Their...
Clinically Stable MS & Magnetic Resonance Imaging MStranslate October 3, 2016 Neuroimaging, Research What is clinically stable multiple sclerosis? As most of you might be aware, the most common form of multiple sclerosis is relapsing-remitting MS (RRMS). In RRMS, people may go through periods of attacks...
